After a three-day assault, Confederate forces under Major General Robert Hoke capture Plymouth, North Carolina.
Outside Plymouth, North Carolina, the Confederate ironclad CSS Albemarle sinks the USS Southfield and damages the USS Miami.
At the Battle of Poison Spring, Confederate forces under Brigadier Generals John S. Marmaduke and Samuel B. Maxey surprise a party of Union soldiers under Colonel James M. Williams, forcing them to retreat without their supplies.
In the aftermath of the Fort Pillow massacre on April 12, Lieutenant General Ulysses Grant orders Major General Benjamin Butler, who was negotiating prisoner exchanges with the Confederacy, to demand that black prisoners had to be treated identical to whites, a demand that was later rejected.
Confederate President Jefferson Davis names General Joseph Johnston commander of the Army of the Tennessee.
Abraham Lincoln announces a grant of amnesty for Emilie Todd Helm, his sister-in-law and the widow of Confederate Brigadier General Benjamin Helm.
Abraham Lincoln issues his Proclamation of Amnesty, which provided an outline of his plan for reconciliation and reconstruction of the Union.
Union forces capture Fort Esperanza, off the coast of Texas.
The Battle of Fort Sanders is fought outside of Knoxville; it is a decisive Union victory; Confederate forces are unable to penetrate Union defensive lines and suffer over 800 casualties.
Confederate General Braxton Bragg, who had been recently defeated outside Chattanooga, telegraphs his resignation to President Jefferson Davis.
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